Ramona Adams
Certara has provided its population-based simulator to support the Environmental Protection Agency‘s toxicity testing program.
The company said Thursday EPA uses Simcyp Simulator to identify commercial chemicals that could pose risks to human health and should be tested further.
Certara CEO Edmundo Muniz said the simulator is designed to simulate the behavior of virtual populations to provide individual variability for EPA’s research.
Simcyp Simulator works to generate variations in human height, weight and blood flow to organs to help EPA predict differences in chemical clearance levels and identify whether a chemical would accumulate or be cleared from the body, Certara noted.
EPA has publicly issued clearance data on 543 chemicals and completed measurements for approximately 200 more.
The company said EPA also started to use Simcyp Simulator in efforts to model pediatric populations.
Certara is a biosimulation and regulatory writing consultancy firm that offers drug development products and services for commercial companies, academic institutions and regulatory agencies.
