He succeeds CEO Thomas Pickens, who will continue to serve as 1st Detect's board chairman, Astrotech said Tuesday.
Mellacheruvu previously worked at ClearCube Technology, Advanced Micro Devices, Omega Band and Noumenon Consulting.
At 1st Detect, he supported the adoption of mass spectrometry technology that contributed to the company's works in the explosives trace detection market.
“We are very pleased to have Raj in his new role as CEO as he leads 1st Detect forward in the adoption of the TRACER 1000 by airports worldwide," said Pickens, who also serves as chairman and CEO of Astrotech.
The company's TRACER 1000 detector uses mass spectrometry to screen cargo and passengers for narcotics and explosive materials.